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Trifluoroacetic anhydride, 99+%, Thermo Scientific Chemicals
CAS: 407-25-0 | C4F6O3 | 210.03 g/mol
28.94€ - 770.84€
Chemical Identifiers
| CAS | 407-25-0 |
|---|---|
| Molecular Formula | C4F6O3 |
| Molecular Weight (g/mol) | 210.03 |
| MDL Number | MFCD00000416 |
| InChI Key | QAEDZJGFFMLHHQ-UHFFFAOYSA-N |
| Synonym | trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove |
| PubChem CID | 9845 |
| SMILES | FC(F)(F)C(=O)OC(=O)C(F)(F)F |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
11473910
|
Thermo Scientific Alfa Aesar
A13614.14 |
25 g |
28.94€
25g |
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|
11460174
|
Thermo Scientific Alfa Aesar
A13614.22 |
100 g |
66.63€
100g |
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|
11470174
|
Thermo Scientific Alfa Aesar
A13614.36 |
500 g |
197.99€
500g |
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|
11480174
|
Thermo Scientific Alfa Aesar
A13614.0E |
2500 g |
770.84€
2500g |
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Description
Trifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrifluoroacetic anhydride is used for the introduction of trifluoroacetyl group in organic synthesis. It is involved in the preparation of N- and O-trifluoroacetyl derivatives of a wide range of biologically active compounds for gas chromatography analysis. It plays an important role as desiccant for trifluoroacetic acid. It is also used in the oxidation of aldehydes to acids, esters, amides as well as in the protection of alcohols and amines. In addition, it is used as analytical reagents, solvents and dehydration condensing agent. It serves as an intermediate of fluorine fine chemicals, pharmaceuticals and agrochemicals.
Solubility
Miscible with benzene, dichloromethane, diethyl ether, dimethylformamide, terahydrofuran and acetonitrile.
Notes
Hygroscopic and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases, strong acids, and alcohols.
Chemical Identifiers
| 407-25-0 | |
| 210.03 | |
| QAEDZJGFFMLHHQ-UHFFFAOYSA-N | |
| 9845 |
| C4F6O3 | |
| MFCD00000416 | |
| trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove | |
| FC(F)(F)C(=O)OC(=O)C(F)(F)F |
Specifications
| 407-25-0 | |
| 1.503 | |
| C4F6O3 | |
| 1.269 | |
| UN3265 | |
| Moisture sensitive | |
| Miscible with benzene,dichloromethane,diethyl ether,dimethylformamide,terahydrofuran and acetonitrile. | |
| FC(F)(F)C(=O)OC(=O)C(F)(F)F | |
| 210.03 | |
| 210.03 | |
| Trifluoroacetic anhydride |
| -65°C | |
| 39°C to 40°C | |
| (CF3CO)2O | |
| MFCD00000416 | |
| 746197 | |
| trifluoroacetic anhydride, trifluoroacetic acid anhydride, 2,2,2-trifluoroacetic anhydride, bis trifluoroacetic anhydride, acetic acid, trifluoro-, anhydride, perfluoroacetic anhydride, trifluoroacetyl anhydride, tfaa, hexafluoroacetic anhydride, anhydrid kyseliny trifluoroctove | |
| QAEDZJGFFMLHHQ-UHFFFAOYSA-N | |
| (2,2,2-trifluoroacetyl) 2,2,2-trifluoroacetate | |
| 9845 | |
| ≥99% |
Safety and Handling
GHS H Statement
H314-H318-H332
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if inhaled.
P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
H314-H332-H335
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missing translation for 'rtecsNumber' : AJ9800000
missing translation for 'tsca' : Yes
Recommended Storage : Keep cold; Store under Nitrogen
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Trifluoroacetic anhydride
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 3
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 A
Hazard Statement
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H332-Harmful if inhaled.
- H412-Harmful to aquatic life with long lasting effects.
- EUH014-Reacts violently with water.
Precautionary Statement
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
- MIXTURE LIST-Contains : Trifluoroacetic acidanhydride
RUO – Research Use Only
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