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SUPV3L1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 12826-1-AP-20UL
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Description
SUV3, also known as SUPV3L1 (suppressor of var1, 3-like 1), is a 786 amino acid protein that localizes to both the nucleus and the mitochondrial matrix and contains one helicase C-terminal domain, as well as one helicase ATP-binding domain. Expressed in a broad range of tissues, SUV3 interacts with HBXIP and functions as an ATPase DNA/RNA helicase that uses magnesium as a cofactor to catalyze the unwinding of DNA/RNA and RNA/RNA duplexes, thereby playing a role in DNA replication and transcriptional initiation. SUV3 exhibits optimal activity at a pH of 5 and, in addition to its helicase activity, is thought to protect cells from apoptosis and participate in maintaining mitochondrial homeostasis.Specifications
| SUPV3L1 | |
| Polyclonal | |
| Unconjugated | |
| SUPV3L1 | |
| SUPV3L1, SUV3, SUV3 like protein 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 294385, 338359, 6832 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunocytochemistry, Western Blot, Immunoprecipitation | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q5EBA1, Q80YD1, Q8IYB8 | |
| Supv3l1 | |
| SUPV3L1 Fusion Protein Ag3542 | |
| 20 μL | |
| Primary | |
| Mouse, Rat, Human | |
| Antibody | |
| IgG |
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