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  6. 10319787

Phleomycin, Fisher BioReagents

Disrupts the integrity of DNA, and blocks S-phase entry in the cell cycle

Brand:  Fisher BioReagents BP2962-100


Quantity 100 mg

Product Code. 10319787

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Description

Description

  • An antibiotic often used as selection agent to determine transformation efficiency of algae, fungi, and mammalian cells
  • Serves as a selection agent for transformed cells carrying the antibiotic-resistance gene Sh ble
  • Causes DNA fragmentation by introducting double-strand breaks in DNA and prevents cells from entering S-phase during the cell cycle
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phleomycin
0.75 to 1.05 AU at 244nm
Streptomyces verticillus
Plastic Bottle
100 mg
QRBLKGHRWFGINE-UGWAGOLRSA-N
2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2S,3R,4R,5S)-4-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)-
72511
Phleomycin
Liquid
11006-33-0
None
Pass Test
C51H75N17O21S2
CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)(C)OC4C(C(C(C(O4)CO)O)(C(=O)N)O)O)C(=O)NC(C)C(C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)C6=NC(=CS6)C(=O)N)O
1326.379
1526.5
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Safety and Handling

Safety and Handling

Product Identifier
  • Phleomycin, 2% solution in water

Signal Word
  • Warning

Hazard Category
  • Carcinogenicity Category 2
  • Respiratory sensitiser Category 1

Hazard Statement
  • H351-Suspected of causing cancer.
  • H317-May cause an allergic skin reaction.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

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