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Dexamethasone, 96%, Thermo Scientific Chemicals
Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.
Brand: Thermo Scientific Acros 230300010
129.15 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.
| Quantity | 1 g |
|---|---|
| Packaging | Glass bottle |
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This item is not returnable.
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Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Information
• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways
Applications
• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.
Chemical Identifiers
| 50-02-2 | |
| 392.47 | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| 5743 | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
| C22H29FO5 | |
| MFCD00064136 | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| CHEBI:41879 |
Specifications
| 50-02-2 | |
| White | |
| Authentic | |
| Glass bottle | |
| MFCD00064136 | |
| 15, 2945 | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| 95% min. (on dried substance) | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | |
| 392.47 | |
| CHEBI:41879 | |
| 96% | |
| Crystalline Powder |
| 255.0°C to 261.0°C | |
| 0.5% max. (105°C, 3 hrs) | |
| 96% | |
| C22H29FO5 | |
| 1 g | |
| + 75.00 | |
| Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one | |
| 5743 | |
| 392.46 | |
| (HPLC) Passes test | |
| Dexamethasone |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Dexamethasone
Signal Word
- Warning
Hazard Category
- Carcinogenicity Category 2
Hazard Statement
- H351-Suspected of causing cancer.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
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