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Dexamethasone, 96%, Thermo Scientific Chemicals
Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.
Brand: Thermo Scientific Acros 230300050
303.40 EUR valid until 2025-12-31
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Quantity | 5 g |
---|---|
Packaging | Glass bottle |
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Descrizione
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Information
• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways
Applications
• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

Identificatori chimici
50-02-2 | |
392.47 | |
UREBDLICKHMUKA-CXSFZGCWSA-N | |
5743 | |
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
C22H29FO5 | |
MFCD00064136 | |
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
CHEBI:41879 |
Specifica
50-02-2 | |
White | |
Authentic | |
Glass bottle | |
MFCD00064136 | |
15, 2945 | |
+ 75.00 | |
Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform | |
UREBDLICKHMUKA-CXSFZGCWSA-N | |
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | |
5743 | |
392.46 | |
(HPLC) Passes test | |
Dexamethasone |
255.0°C to 261.0°C | |
0.5% max. (105°C, 3 hrs) | |
96% | |
C22H29FO5 | |
5 g | |
+ 75.00 (20.00°C c=1,dioxane) | |
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
95% min. (on dried substance) | |
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | |
392.47 | |
CHEBI:41879 | |
96% | |
Crystalline Powder |
Sicurezza e movimentazione
- Dexamethasone
Avvertenza
- Warning
Categoria di pericolo
- Carcinogenicity Category 2
Indicazioni di pericolo
- H351-Suspected of causing cancer.
Consigli di prudenza
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
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