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Thermo Scientific Chemicals Cloxacillin sodium salt monohydrate
Cloxacillin sodium salt monohydrate, CAS # 7081-44-9, is a compound that targets gram-positive bacteria and shows antibacterial activity.
Brand: Thermo Scientific Chemicals 455300050
| Quantity | 5 g |
|---|
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Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Cloxacillin sodium salt monohydrate is a chlorinated derivative of oxacillin that shows β-lactamase-resistant antibiotic activity
• This compound inhibits the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which results in cell lysis, that is mediated by bacterial cell wall autolytic enzymes
Applications
• Cloxacillin sodium salt monohydrate targets gram-positive bacteria, and is effective against staphylococci that produce β-lactamase
• It acts in vitro against both penicillin gram-resistant and gram-sensitive staphylococci, certain streptococci, and pneumococci
• This compound is commonly used in vivo and in vitro studies as AmpC β-lactamase inhibitor in combination with β-lactam antibiotics
Chemical Identifiers
| 7081-44-9 | |
| 475.876 | |
| 23675743 | |
| sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate |
| C19H19ClN3NaO6S | |
| KCUWTKOTPIUBRI-VICXVTCVSA-M | |
| CHEBI:34978 | |
| CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+] |
Specifications
| Cloxacillin Sodium Salt Monohydrate | |
| Authentic | |
| 5 g | |
| KCUWTKOTPIUBRI-VICXVTCVSA-M | |
| sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate | |
| 23675743 | |
| 475.88 | |
| Cloxacillin sodium salt monohydrate |
| 7081-44-9 | |
| 3.0 to 5.0% | |
| C19H19ClN3NaO6S | |
| CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+] | |
| 475.876 | |
| CHEBI:34978 | |
| ≥94% (HPLC) |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- Cloxacillin sodium salt monohydrate
Signal Word
- Danger
Hazard Category
- Serious eye damage/eye irritation Category 2
- Respiratory sensitiser Category 1
- Skin corrosion/irritation Category 2
- Skin sensitiser Category 1
- Specific target organ toxicity Category 3
Hazard Statement
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- H315-Causes skin irritation.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
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