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A23187, 98%, free acid, Thermo Scientific Chemicals
A23187 (Calcimycin), CAS # 52665-69-7, is a calcium ionophore-based antibiotic.
Brand: Thermo Scientific Acros 328080010
51.66 EUR valid until 2025-12-31
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Quantity | 1 mg |
---|---|
Packaging | Glass Bottle in Plastic Container |
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Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• A23187 is a polyether substance that permeabilizes cell membranes to calcium and other divalent cations
Applications
• A23187 can be used for the study of mitochondrial physiology because it acts as an uncoupling agent
• A23187 can be used to study the roles of divalent cations in cell physiology
• When bound to fluorescent calcium ions, A23187 can be useful for imaging studies

Chemical Identifiers
52665-69-7 | |
523.63 | |
HIYAVKIYRIFSCZ-CVXKHCKVSA-N | |
5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid |
C29H37N3O6 | |
MFCD00151202,MFCD00151202 | |
97043288 | |
CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O |
Specifications
Solid | |
97.5 | |
182.0°C to 193.0°C | |
Glass Bottle in Plastic Container | |
1 mg | |
C29H37N3O6 | |
15, 1642 | |
HIYAVKIYRIFSCZ-CVXKHCKVSA-N | |
5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid | |
97043288 | |
98% |
52665-69-7 | |
100.0 | |
Authentic | |
White | |
98% | |
MFCD00151202,MFCD00151202 | |
Solubility in water: .. Other solubilities: soluble in dmso, ethylacetate, methanol, ethanol | |
CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O | |
523.63 | |
523.63 | |
A23187, Free acid |
Safety and Handling
- A23187 (free acid)
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
- H312-Harmful in contact with skin.
- H332-Harmful if inhaled.
- H302-Harmful if swallowed.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
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